Investigation of the Antimicrobial Activity of Some Streptomyces spp. Isolated from Nineveh Province
DOI:
https://doi.org/10.24126/jobrc.2010.4.2.116Keywords:
Actinomycetes, Streptomyces, AntibioticsAbstract
Atotal of 62 different Streptomyces isolates were recovered from 17 samples of soil collected from different sites of Nineveh Province. Only 23 isolates showed activity against test Gram-positive and Gram-negative bacteria. One isolate showed high antimicrobial activity against Staphylococcus aureus, was selected and identified as Streptomyces lavendulae on the bases of microscopic, morphologic, biochemical tests and its sensitivity to some antibiotics. The bioactive compound produced by S. lavendulae was isolated on TLC plate (Rf 0.85). The UV spectrum of the active compound in methanol showed one peak at 280 nm. From these data it could be concluded that the active compound probably belongs to macrolide antibiotics group.
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