Effect of static magnetic fields against some virulence factor of C.albicans: germ tube formation, adhesion ability and biofilm formation

Abstract

In vitro, inhibitory effects of static magnetic fields in the type of two poles and negative and positive pole on some virulence factors belong to C.albicans as pathogenic microorganism was investigated in this study. According to the findings of this study static magnetic fields in the type of two poles and negative pole displayed a variable degree of inhibitory effects against this microorganism via its virulence factors such as: germ tube formation, adhesion ability and biofilm formation in which negative pole showed more strongly effect than two poles as inhibitory values ranged from 35% as germination ability, 30% adhesion ability after 3hrs of treatment and 2.2mg/disk dry weight as biofilm formation after 72hrs of treatment compared with the inhibitory values for two poles ranged from 30% as germination ability, 25% adhesion ability after 3hrs of treatment and 2.7mg/ disk dry weight as biofilm formation after 72hrs of treatment . Following our earlier demonstration, the effects of positive pole also investigated in this study as 10 % for germination ability, 10% adhesion ability after 3hrs of treatment and 3mg/ disk dry weight as biofilm formation after 72hrs of treatment. These results revealed that static magnetic fields in the type of negative pole may be useful as antifungal agent against Candida albicans.