Immune Enhancing Effect of Lactobacillus acidophilus and Lactobacillus gasseri in Mice Infected with Salmonella typhimurium
DOI:
https://doi.org/10.24126/jobrc.2014.8.3.365Keywords:
Immune effect, Lactobacillus, Salmonella typhimuriumAbstract
This study was carried out to assess the protective immune effect of mixed culture of Lactobacillus acidophilus and Lactobacillus gasseri in mice infected with Salmonella typhimurium. Parameters of evaluation were total and absolute count of leukocyte and phagocytosis. Fifteen albino mice divided into five groups and designated as follows: CG used as negative control, SG was infected with 0.1 ml Salmonella typhimurium 2.5×107 cfu/ml and used as a positive control, AC was treated with 0.1ml Lactobacillus acidophilus 1×109 cfu/ml and infected with Salmonella typhimurium 2.5×107 cfu/ml, GG was doused with Lactobacillus gasseri and infected with Salmonella typhimurium, AG was fed with 0.1 ml mixed culture of Lactobacillus acidophilus and Lactobacillus gasseri 1×109 cfu/ml and infected with Salmonella typhimurium 2.5×107 cfu/ml. Results indicated that mice treated with viable Lb.acidophilus and Lb.gasseri showed a significant protective immune effect compared with positive and negative control, while mice fed with mixed culture of Lb.acidophilus and Lb.gasseri exhibited less protective effect against Salmonella typhimurium compared with groups fed with monoculture of Lactobacillus.
Downloads
Published
How to Cite
Issue
Section
License
This is an Open Access article distributed under the terms of the creative commons Attribution (CC BY) 4.0 license which permits unrestricted use, distribution, and reproduction in any medium or format, and to alter, transform, or build upon the material, including for commercial use, providing the original author is credited.