Study the Relationship Between Obesity and Fertility in Diabetic Iraqi Men

Abstract

The aim of the present study is to investigate the relationship between obesity and fertility in Iraqi
diabetic men whose body mass index (BMI) more than 25Kg/m2
, and compare the results with control
group corresponding age and BMI. Forty samples of men semen's were divided into two groups with and
without diabetes and each group subdivided into two subgroups according to BMI. The parameters that
measured in this study are( glucose, insulin and lipid profile in fasting state) also (testosterone, prolactin,
alkaline phosphatase) were measured for each of four subgroups [controls(I, II) and diabetes(III, IV)].
Semen's analysis included (sperm concentration in ml, total count per ejaculate and viability). In diabetic
subgroup (III) the mean levels of fasting blood glucose, insulin, cholesterol and triglycerides were
significantly elevated, while significantly decrease in testosterone, prolactin, high density lipoproteinscholesterol, alkaline phosphatase and total sperm count but there were no significant difference in total
cholesterol, the sperm concentration and viability as compared with control subgroup(I). In diabetic
subgroup (IV) the mean levels of fasting blood (glucose, insulin, cholesterol and triglycerides) were
significantly elevated, while significantly decrease in (testosterone, prolactin, high density lipoproteinscholesterol, alkaline phosphatase, sperm concentration, viability and total sperm count) but there were no
significant difference in fasting (insulin and high density lipoproteins- cholesterol) as compared with
control subgroup(II). In diabetic subgroup(III) the mean of BMI and the mean levels of fasting blood
(glucose, total cholesterol and triglycerides) significantly elevated, while there were significantly decrease
in(testosterone, alkaline phosphatase, sperm concentration, viability and total sperm count but there were
no significant difference in fasting (insulin, high density lipoproteins- cholesterol) and prolactin, as
compared with diabetic subgroup(IV). For all the above biochemical parameters investigated we can
conclude that there is inverse- relationship between obesity and fertility which increase in the presence of
diabetes.