Serum High-Sensitivity C-Reactive Protein and Endogenous Sex Hormones in Diabetic Men
DOI:
https://doi.org/10.24126/jobrc.2016.10.1.463Keywords:
diabetes mellitus type 2, hs-CRP, FSH, testosteroneAbstract
The objective of this cross sectional study was to assess the effect of diabetes mellitus (DM) type 2 in men on endogenous sex hormones: estradiol (E2) and total testosterone (TT); pituitary gland hormones: follicle-stimulating hormone (FSH) and luteinizing hormone (LH) as well as high sensitive C-Reactive protein (hs-CRP) in men. This study comprised a total of (80) subjects out of which (40) were normal and (40) were diabetic males. The results obtained indicated a significant increasing (p≤ 0.05) of serum hs-CRP and E2 in men with DM type 2 comparison to non-diabetics, while a significant reduction (p≤ 0.05) of serum testosterone in men with DM type 2 comparison to non-diabetics, and non-significant reduction of serum LH, FSH in men with DM type 2 comparison to non-diabetics were observed. The data from this study show the role of endogenous sex hormones and hs-CRP in diabetes risk. Testosterone levels are partly influenced by insulin resistance, which may represent an important avenue for intervention
Downloads
Published
How to Cite
Issue
Section
License
This is an Open Access article distributed under the terms of the creative commons Attribution (CC BY) 4.0 license which permits unrestricted use, distribution, and reproduction in any medium or format, and to alter, transform, or build upon the material, including for commercial use, providing the original author is credited.