Serum High-Sensitivity C-Reactive Protein and Endogenous Sex Hormones in Diabetic Men

Authors

  • Shakir F.T. Al-Aaraji

DOI:

https://doi.org/10.24126/jobrc.2016.10.1.463

Keywords:

diabetes mellitus type 2, hs-CRP, FSH, testosterone

Abstract

The objective of this cross sectional study was to assess the effect of diabetes mellitus (DM) type 2  in men on endogenous sex hormones: estradiol (E2) and  total testosterone (TT); pituitary gland hormones: follicle-stimulating hormone (FSH) and luteinizing hormone (LH)  as well as high sensitive C-Reactive protein (hs-CRP) in men. This study comprised a total of (80) subjects out of which (40) were normal and (40) were diabetic males. The results obtained indicated a significant increasing (p≤ 0.05) of serum hs-CRP and E2 in men with DM type 2 comparison to non-diabetics, while a significant reduction (p≤ 0.05) of  serum testosterone in men with DM type 2 comparison to non-diabetics, and non-significant reduction of serum LH, FSH in men with DM type 2 comparison to non-diabetics were observed. The data from this study show the role of endogenous sex hormones and hs-CRP in diabetes risk. Testosterone levels are partly influenced by insulin resistance, which may represent an important avenue for intervention

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Published

2016-01-03

How to Cite

Al-Aaraji, S. F. . (2016). Serum High-Sensitivity C-Reactive Protein and Endogenous Sex Hormones in Diabetic Men. Journal of Biotechnology Research Center (JOBRC), 10(1), 48–52. https://doi.org/10.24126/jobrc.2016.10.1.463

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Section

Research articles