Histopathological Effects of Tilletia fungus Spores Causing Wheat Smut on the Stomach, Intestines and Heart of Experimental Mice

Authors

  • Eman Jwad Kadhum
  • Adel Abed Hasony
  • Neamat Jameel

DOI:

https://doi.org/10.24126/jobrc.2009.3.2.59

Keywords:

Histopathological effect, Tilletia spores, Wheat smut

Abstract

Oral dose and intraperitonial injection of 30 experimental mice with spore suspension of Tilletia fungus revealed different clinical signs, included decrease in body weight, emaciation, general weakness, dyspenia, and ataxia. Severity of these changes depend upon concentration of spore suspension. While histopathological effects on heart, stomach and intestine of these experimental mice, were seen at concentration of 0.1 milligram / 0.5 milliliter PBS of spore suspension. Oral dose revealed more histopathologic damage in stomach, and intestine tissue than intraperitonial injection. Oral dose of 0.1 milligram /0.5 milliliter PBS caused mucous epithelium sloughing or detachment squamation accompanied with formation of ulcers oedema damage and necrosis, on the other hand, intraperitonial injection caused epithelium detachment with ulceration.

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Published

2009-06-01

How to Cite

Kadhum, E. J. ., Hasony, A. A. ., & Jameel, N. . (2009). Histopathological Effects of Tilletia fungus Spores Causing Wheat Smut on the Stomach, Intestines and Heart of Experimental Mice. Journal of Biotechnology Research Center, 3(2), 5–14. https://doi.org/10.24126/jobrc.2009.3.2.59

Issue

Vol. 3 No. 2 (2009): Issue 2

Section

Research articles

License

This is an Open Access article distributed under the terms of the creative commons Attribution (CC BY) 4.0 license which permits unrestricted use, distribution, and reproduction in any medium or format, and to alter, transform, or build upon the material, including for commercial use, providing the original author is credited.