Cytogenetic effect of lactobacillus acidophilus concentrated filtrate on albino mice bone marrow cells

Authors

  • Ebtehal H. Al-Naimie
  • Ruqia M. Al-Azy
  • Muthanna A.S. Al-Mahdawii

DOI:

https://doi.org/10.24126/jobrc.2009.3.2.63

Abstract

This study deals with the cytogenetic effect of lactobacillus acidophilus concentrated filtrate on metaphase index of bone marrow cells in mice. Cyclophosphamide is a drug that is used primarily for treating several types of cancer. In order to work, cyclophosphamide first is converted by the liver into two chemicals, acrolein and phosphoramide. The results showed that lactobacillus acidophilus concentrated filtrate caused a significant increased in metaphase index in comparison with the negative control (distilled water) and positive controls (Cyclophosphamide) especially at high doses. The results of interaction study showed that pre- and post-treatment with lactobacillus acidophilus concentrated filtrate caused a significant increased in metaphase index of mice bone marrow cells

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Published

2009-06-01

How to Cite

Al-Naimie, E. H. ., Al-Azy, R. M. ., & Al-Mahdawii, M. A. . (2009). Cytogenetic effect of lactobacillus acidophilus concentrated filtrate on albino mice bone marrow cells. Journal of Biotechnology Research Center, 3(2), 23–29. https://doi.org/10.24126/jobrc.2009.3.2.63

Issue

Vol. 3 No. 2 (2009): Issue 2

Section

Research articles

License

This is an Open Access article distributed under the terms of the creative commons Attribution (CC BY) 4.0 license which permits unrestricted use, distribution, and reproduction in any medium or format, and to alter, transform, or build upon the material, including for commercial use, providing the original author is credited.