The relation between vitamin D insufficiency and thyroid hormones in Iraqi women living in Al-Khalidiya, Anbar Province

Abstract

Background: Vitamin D insufficiency is a worldwide issue in all age groups. It was
discovered that vitamin D insufficiency is linked to autoimmune disorders such as Irritable
bowel illness, rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, and
rheumatoid arthritis. Vitamin D is also connected to the development of thyroid autoimmune
disease and plays an important role in endocrinopathies including type 1 and type 2 diabetes,
adrenal diseases, and polycystic ovarian syndrome.
Materials and methods: 100 samples were collected for women from Al-Khalidiya city in
Anbar province (50 samples likely to have thyroid problems, 50 healthy samples). The levels
of vitamin D and thyroid hormones were measured using A Minividus system (which
combines a two-step enzyme sands assay with an ELFA, or End Fluorescent Detection
Method).
Results: The current findings revealed that there are significant variations in vitamin D and
T4 levels between patients and healthy controls ( P-value 0.05). There is also a positive
association between vitamin D levels and T4 (r = 0.378, P-value = 0.007), as well as a
negative correlation between vitamin D levels and TSH (r = -0.373, P-value = 0.008).
Conclusion: According to our result, Individuals with hypothyroidism in Alkhaldia have a
vitamin D3 deficiency. In addition, blood vitamin D levels show a positive correlation with T4
and a negative correlation with TSH levels. To avoid developing osteoporosis if
hypothyroidism persists, all hypothyroid Iraqi patients should be checked for Vitamin D
deficiency.