Bacteriological Study of salivaricin production from treptococcus salivarius isolated from the oral cavity

Abstract

A total of 115 samples (oral cavity swabs) were collected from healthy individuals. Sixty eight isolates were identified as Streptococcus salivarius using microscopical, biochemical and serotyping tests. The ability of Streptococcus salivarius local isolates to produce salivaricin was detected by testing the inhibitory activity against gram positive bacteria and gram negative bacteria. Results showed that only 26 isolates were capable of producing salivaricin and showed inhibitory activity against some gram positive isolates especially S. pyogenes, while no inhibitory effect was noticed towards the gram negative isolates that were used in this study. S. salivarius IS9 was selected according to its efficiency of inhibiting activity against a number of tested bacteria.The results of determination of antagonistic effect of IS9 against all local isolates of S. salivarius showed that 45 isolates of them were affected, while 23 isolates were not affected.